Resources

Facilities

Cell Therapy Incubator 

Designed to host high-specialty programs for early stage development, academic research teams and small biotechnology companies which typically do not have the resources to justify large capital investments for the build-out of facilities and infrastructure, the Cell Therapy Incubator is housed in a 1,150 sq.-ft. laboratory space adjacent to the main manufacturing facility that includes:

  • A 535 sq.-ft. wet lab
  • 345 sq.-ft. clean room suite
    • 73 sq.-ft. gowning vestibule
    • 272 sq.-ft. clean room for processing
    • Clean room and vestibule are connected by a pass-through window unit to permit controlled introduction of materials without need for staff to open the entry door
  • 118 sq.-ft. secured storage space
  • 150 sq.-ft. HVAC room
  • Twenty-four hour facility monitoring for ambient temperature and humidity, freezers and air pressure

Cleveland Cord Blood Center

Located on the eastside of the Cleveland, Ohio, metropolitan area, the Cleveland Cord Blood Center (CCBC) is a 2,680 sq.-ft. processing facility with designated, separated areas committed to cord blood unit receipt, accessioning, pre-processing and processing activity, sampling for release testing and cryopreservation.

The clean room suite features a Class 10,000 (ISO 7) clean room and an adjacent Class 100,000 (ISO 8) gowning room.

Facilities are designated to facilitate cGMP compliance and includes adequate space for separation of processes, unidirectional workflow, and surfaces that are easily cleaned.

Administrative, IT and quality team members are housed in adjacent offices to the processing facility.

Equipment

  • Three Class II, Type A2 Laminar Flow Biosafety cabinets
  • Two Sysmex XE 2100 Hematology analyzers
  • BD FACS Canto II Flow cytometer 
  • AXP cell processing devices (Cesca Therapeutics, formerly Thermogenesis)
  • Four BioArchive LN2 Dewars (Cesca Therapeutics)
  • Variant II isoelectric focusing instrument (BioRad Hb)
  • Two BioMerieux BacTAlert 3D culture systems
  • Miltenyi autoMACs cell sorter
  • Coulter ZM counter
  • Magnetic separation systems
  • Hypoxia chamber
  • Spectromax 250 visible plate reader
  • BioRad Gel Doc 1000
  • BioRad ChemiDoc XRS